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In terms of bodybuilding, ostarine can be used either on cycle or off-cycle to help keep and increase lean muscle mass, while also burning fat.[21][22]
In terms of bodybuilding, ostarine can be used either on cycle or off-cycle to help keep and increase lean muscle mass, while also burning fat.
The most well known application of ostarine is in the management of chronic pain, human growth hormone 10 iu. Although it has been used in pain management, the drug has also demonstrated potential in enhancing and increasing the efficacy and safety of opioids such as morphine (used in pain control), oxycodone (pain reliever) or hydromorphone (pain reliever) or as a first drug in some treatments for drug addiction like methadone maintenance therapy.[23] In a study of methadone maintenance therapy to chronic pain, a reduction in the opiate effect of methadone was observed.[19]
Ostarine may have been found to have some value as a first drug for pain management
13.2. Neurological
Ostarine is known to be an inhibitory neurotransmitter in the central nervous system that seems to underlie the effects of anabolic steroids, which may be due to the drug's ability to cause a reduction in the excitability/activity of neurons. A study conducted by Ziegler showed ostarine can act as an inhibitor of the GABAergic and serotoninergic neurotransmitters[3];[2] when tested over a period of 2 years of using ostarine, GABA was reduced, while in a second study on ostarine there was an increase in the density of the dopamine transporter (dAT) at the site of ostarine binding, which is thought to have neuroprotective properties.[4] GABA is the main inhibitory neurotransmitter in the central nervous system (CNS), ostarine cycle results.[24]
Ostarine at a concentration of 100nM was investigated in vitro and was found to be slightly (and nonsignificantly) inhibitory on dopamine transporter, human growth hormone 10 iu.
14 Safety and Toxicology
14, results ostarine cycle.1, results ostarine cycle. General
Ostarine is one of the most well-known anabolic steroids, known to induce several human health benefits and to be a potent anabolic/androgenic steroid[2]:
It can increase muscle size (in the absence of strength training or prolonged exercise[2]), which occurs when oral supplementation is coupled with heavy lifting
Ostarine does not have any acute toxicity
Ostarine can be detected in human urine following a low dose injection (10-50mg)
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